Session 1095: Multidrug Resistance - MDR
Cochair(s): L Coussens, C Dittrich
Date: Sun 10 February 2002,
Time: 14:00 - 15:30
Location: Amphithéâtre Duclaux
Oral Presentations
| Time |
Number |
Title / Authors / Affiliations |
| 14:00 |
447 |
Proteasome
inhibition as a novel approach to cancer
therapy
J Adams
Millennium
Pharmaceuticals, Inc, Cambridge,
Massachusetts |
| 14:15 |
448 |
The lambda-Int
family recombinases, Cre and Flp are inhibited by
topoisomerase I targeting anticancer
drugs
RF Frøhlich, SG Hansen, FF Andersen, JR Olesen, M
Jayaram, O Westergaard, BR Knudsen
1Department
of Molecular and Structural Biology, University of
Aarhus, Aarhus, Denmark, 2Section of Molecular
Genetics and Microbiology, University of Texas, Austin,
TX |
| 14:30 |
449 |
Molecular basis
of the ability of new antitumour agents -
benzoperimidines and anthrapyridones - to overcome
multidrug resistance.
J Tarasiuk, B Stefanska, K Tkaczyk-Gobis, A
Garnier-Suillerot, E Borowski
1Department
of Pharmaceutical Technology and Biochemistry, Technical
University of Gdansk, Poland, France,
2Laboratoire de Physicochimie Biomoleculaire
et Cellulaire, 3Universite Paris Nord, Paris,
France, 4Department of Biochemistry,
University of Szczecin, Poland |
| 14:45 |
450 |
Genomic gain and
loss associated with drug-resistance of CCRF-CEM leukemic
cells
T Efferth, I Verdorfer, A Sauerbrey, H Miyachi, CR
Chitambar, HG Drexler, E Gebhart
Virtual Campus
Rhineland-Palatinate, Mainz, Germany |
| 15:00 |
451 |
The cyclosporin
PSC 833 prolongs survival of NOD-SCID mice following
xenotransplantation with human myeloblasts carrying
P-glycoprotein
G Lehne, D Sørensen, GE Tjønnfjord, C Beiske, HE Rugstad,
T-A Hagve, OPF Clausen
1Department
of Clinical Pharmacology, Department of Comparative
Medicine, 2Department of Clinical
Pharmacology, Department of Internal Medicine,
3Department of Clinical Pharmacology,
Institute for Pathology, 4Department of
Clinical Pharmacology, and Department of Clinical
Chemistry, 5Department of Clinical
Pharmacology; Rikshospitalet University Hospital, Oslo,
Norway |
| 15:15 |
452 |
DNA
methyltransferase-3b is preferentially expressed in drug
resistant cells
RS Dwivedi, Y-Y Qiu, BL Mirkin
Childrens Memorial
Institute for Education and Research, Childrens Memorial
Hospital and Department of Pediatrics, Northwestern
University Medical School, Chicago, USA [ok] |
Poster Presentations
| Number |
Title / Authors / Affiliations |
| 453 |
Evaluation of
multidrug resistance in in vitro treated cells of
cancerous patients versus healthy donors by single cell
gel electrophoresis assay (SCGE) assay.
P Poli, A Buschini, C Alessandrini, A Martino, L Pasini,
V Rizzoli, S Bonomini, C Rossi
1Istituto di
Genetica, 2Cattedra di Ematologia; Università
di Parma, Italy |
| 454 |
The activity of
latent benzoperimidine esters to inhibit P-glycoprotein
and MRP1 dependent efflux of pirarubicin from several
lines of multidrug resistant tumour
cells.
D Glowacka-Rogacka, M Arciemiuk, A Kupiec, MM
Bontemps-Gracz, E Borowski, J Tarasiuk
Department of
Pharmaceutical Technology and Biochemistry, Department of
Biochemistry, Technical University of Gdansk, Poland,
Poland |
| 455 |
The effect of new
antitumor agents on the energy metabolism of human
erythrocytes.
R Nowak, I Baranowska-Bosiacka, B Stefanska, J Hlynczak,
J Tarasiuk
1 Department of
Biochemistry, Poland 2 Department of Pharmaceutical
Technology and Biochemistry, University of Szczecin,
Technical University of Gdansk, Poland |
|
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