Omega-3 fatty acids supplemented with curcumin and rosemary extracts provide support to cancer patients

M Shinitzky^a, J Dayan^b, D Yam^a

^aWeizmann Institute of Science, Rehovot, Israel, ^bspecialist in Internal Medicine, Rehovot, Israel

Introduction - EPA and DHA omega-3 polyunsaturated fatty acids (n-3 PUFA), in contrast to n-6 PUFA, have been shown to have anticancer activities. In addition, recent studies, attributed to curcumin and rosemary (extracted from Curcuma species and Rosemarinus officinalis), anti-inflammatory, anti-oxidative and anti-tumor activities, which lead to cancer cells apoptosis. According to our evaluation, cancer patients should consume 8-10 grams/d of omega-3 PUFA. To reach these high dietary levels of n-3, and curcumin and rosemary extracts, Yamega Ltd – Israel, has developed a unique paste that can be used as a bread spread or as other convenient intakes. Objective of the research: To verify the effect of the consumption of the paste on cancer patients. Research design: The study was conducted in collaboration with hospitals and clinics with the participation of 42 patients with generalized solid tumors submitted to therapy, and 6 resistent to therapy. Each participant was instructed to consume 10 gr/d of Yamega spread, and to avoid the consumption of glucose, sucrose and omega-6 oils for a period of six months. Results: No side effects and no gastro-intestinal discomfort were noticed. Participants statements indicate better quality of life, normal blood glucose, triglycerides and cholesterol. No cachexia. Better tolerance to chemotherapy with a lower level of side effects. At least half of the patients show lower consumption of analgesia. High compliance rate. Conclusions: The supplementation of Yamega’s spread may provide significant palliative support to cancer patients. The supplementation of omega-3 PUFA as cancer prevention merit serious consideration

Paper presented at the International Symposium on Predictive Oncology and Intervention Strategies; Nice, France; February 7 - 10, 2004; in poster session 793 (Dietary Influences).