Session 893: Predictive molecular pathology

Date: 2 February 2004, Time: 11:30 - 13:30
Location: Room 3

Oral Presentations

Time	Number	Title / Authors / Affiliations
11:30	20	Alterations of p16INK4a, p14ARF, p53, PCNA expressions and their relationship to HPV infection in the tumor progression of cervical cancer JL Wang MD PhD^a, BY Zheng MD^a, M Lindström BSc^b, K-L Wallin PhD^a ^aDepartment of Molecular Medicine, ^bDepartment of Oncology-Pathology; Karolinska Institute, Stockholm, Sweden
11:45	21	Enhancing Pap test with a new biological marker of cellular dysplasia with MarkPap™ Test N Markovic MD PhD, P Emer, O Markovic MD PhD Prof BioSciCon, Inc, Rockville, MD, United States
12:00	22	Validation of prognostic molecular markers in malignant pleural mesothelioma GJ Gordon PhD, R Bueno MD Division of Thoracic Surgery, Brigham and Women’s Hospital and Harvard Medical School, Boston MA, United States
12:15	23	The loss of histidine decarboxilase activity of plasma cells infiltrating the skin in a case of therapy resistant multiple myeloma. A common characteristic of epidermoinvasive malignant B-cell J Varkonyi, MD, PhD *(a); K Szocs; A Vereczkei, MD, PhD; I Karadi, MD, DSCI; Z Sapi, MD, DSCI(b); M Marschalko, MD, PhD(a); I Kovacs (c); Z Darvas, PhD; A Falus, DSCI ^aSemmelweis University Medical School, Budapest, Hungary, ^bDepartment of Pathology, St. Juhns's Hospital, Budapest, Hungary, ^cKenezy Gyula County Hospital, Debrecen, Hungary
12:30	24	Predictive value of immunohistochemical detected melanoma satellite metastases N Claessens MD, JE Arrese PhD, GE Piérard PhD Department of dermatopathology, University of Liège, Liège, Belgium
12:45	25	Timing breast cancer surgery and methylation status of genes in relation to the phase of the menstrual cycle. VH Deshmane^a, IS Fentiman^b, IR Hart^c ^aDepartment of Surgical Oncology, Hinduja Hospital, Mumbai, India, ^bBreast Unit, Guy’s Hospital, London, United Kingdom, ^cDepartment of Tumour Biology, Queen Mary's School of Medicine and Dentistry, Barts and The London, London, United Kingdom
13:00	261	Saffron as potential candidate for cancer chemoprevention trials FI Abdullaev PhD Laboratory of Experimental Oncology, National Institute of Pediatrics, Mexico D.F, Mexico

Poster Presentations

Number	Title / Authors / Affiliations
39	Clinical relevance of DNA-ploidy for liver transplantation due to hepatocellular carcinoma H Al-Abadi MD, G Schumacher MD, S Jonas MD, J Langrehr, CTIAC Rotter, P Neuhaus MD General-, Visceral- and Transplantation Surgery, Laboratory of Clinical Cytology and DNA-cytometry, Charité, Campus Virchow-Klinikum, Humboldt University, Berlin, Germany.
40	Histone deacetylase inhibitor, FR901228, prevents the development of adjuvant arthritis in rats T Nakamura MD^a, A Kukita PhD^a, T Shobuike PhD^a, T Kakimoto^a, T Kukita PhD^b, O Kohashi MD PhD^a ^aDepertment of Pathology and Biodefense, Saga University, Saga, Saga, Japan, ^bSection of Oral Cellular and Molecular Biology, Divition of Oral Biological Science, Kyushu University, Fukuoka, Fukuoka, Japan
41	Non-synonymous cSNP and InDel discovery by bioinformatic data mining CH Lai MS, LY Hu MS, JY Chiu MS, W-C Lin PhD Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan
42	Slot- and Western blot immunoassays of poly-ADP-ribosylation of mouse blood lymphocyte proteins and initiation of carcinogenesis: A possible screening tool for early detection of cancer RN Sharan PhD Radiation and Molecular Biology Unit, Department of Biochemistry, North-Eastern Hill University, Shillong 793 022, Meghalaya, India
43	Expression of CD44V6 gene in normal human peripheral blood J Song, D Zhang, J Zheng PhD Department of Pathology, Institute of Molecular Pathology, Medical School of Southeast University, Nanjing，210009, PR, China
44	Fluorescent spectral analysis of cells in cancer control strategies NA Karnaukhova, MSD Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, 142290, Russia
45	Enzymatic method for selective determination of acetylpolyamine as a biomarker K Tomita PhD, S Sakurada MS, T Sugiyama MS, K Kutsuzawa MS, S Isomura Kanto Gakuin University, Yokohama, Japan
46	Allelotyping analysis of GEP endocrine tumors S Uccella MD, D Furlan BSc, R Cerutti BSc, S La Rosa MD, C Capella MD Department of Clinical and Biological Sciences, University of Insubria, Varese, Italy
47	Development of monoclonal antibodies for detecting hemidesmosomal proteins, bullous pemphigoid antigen 2 (BPAG2) and &alpha6 integrin: Expression of BPAG2 in epidermal malignancies MD Marczinovits PhD^a, T Krenacs PhD^d, E Stelkovics^d, MD Korom^b, M Kiss PhD^b, S Husz MD DSc^b, G Toth DSc^c, K Rasky PhD^e, J Molnar MD DSc^a ^aUniversity of Szeged, Szeged, Hungary, ^bDermatology, Szeged, Hungary, ^cMedical Chemistry, Szeged, Hungary, ^dBay Zoltan Foundation for Applied Research, Szeged, Hungary, ^eDiagnosticum Co, Budapest, Hungary
48	Expression of E-cadherin and alpha-catenin in esophageal squamous cell carcinomas T Setoyama, S Natsugoe, H Okumura, T Aikou Department of Surgical Oncology and Digestive Surgery, Graduate School of Medicine, Kagoshima University, Kagoshima, Japan
49	Lymphocytes subtypes expression and prognosis of squamous cell carcinoma of the lower lip G Fabbrocini^a, S Staibano^b, P Somma^b, G Mansueto^b, G De Rosa^b, M Delfino^a, P Santoianni^a ^aDepartment of Systematic Pathology -Section of Dermatology, ^bDepartment of Biomorphologic and Functional Sciences, Section of Pathology; University of Naples Federico II, Naples, Italy
50	Sporosis: A Source of undifferentiated cells in the human sarcoma line HT-1080 PhD Buikis^a, T Freivalds PhD^a, L Harju^a, S Nikulshin MD^b ^aUniversity of Latvia Institute of Experimental and Clinical Medicine, Riga, Latvia, ^bLatvian National Hematology Center, Riga, Latvia
51	Amplification and sequence changes in epidermal growth factor receptor (EGFR) gene in glioblastomas D Arjona, BSc(a)*; ME Alonso, BSc(a); P González-Gómez, BSc(a); I Lopez-Marin, SciTech(a); M Gutiérrez, MD, PhD(b); JM deCampos, MD, PhD(c); J Vaquero, MD, PhD(d); A Villalobo, MD, PhD(e); MJ Bello, PhD(a); JA Rey, PhD(a) ^aLab. Oncogenética Molecular, Dpt. C. Experimental and, Pº Castellana 261, Madrid, ^bDpt. Anatomía Patológica, Hospital Universitario La Paz, Pº Castellana 261, Madrid, Spain, ^cDpto. Neurocirugía, Hospital del Río Hortega, Valladolid, Spain, ^dDpt. Neurocirugía, Hospital Puerta de Hierro, Madrid, Spain, ^eInstituto Investigaciones Biomédicas, CSIC, Madrid, Spain
52	DAP-kinase hypermethylation study in brain metastases of solid tumors. P González-Gómez BSc^a, ME Alonso BSc^a, NP Anselmo PhD^b, D Arjona BSc^a, C Amiñoso, S Tech^a, A Isla MD PhD^c, JL Sarasa MD PhD^d, C Casartelli PhD^b, JA Rey PhD^a, MJ Bello PhD^a (a) Lab.Oncogenetica Molecular, Dpt. Cir. Experimental. Hospital Universitario La Paz, Madrid, Spain. (b) Dpt. Genetica ,Universidad de Sao Paolo. Riberao Preto (Sao Paolo). Brazil. (c) Dpt. Neurocirugía, Hospital Universitario La Paz, Madrid, Spain. (d) Dpt. Neurocirugía, Hospital del Río Hortega, Valladolid, Spain.
53	Prognostic implication of clinical, radiological, and pathological features in patients with oligodendroglial tumors. A Tortosa MD PhD^a,d, M Brell MD^b, P Teixidor MD^b, JJ Acebes MD PhD^b,d, L Caral MD^c, JM Gil MD^b, T Pujol MD^c, T Ribalta MD PhD^c,d, E Verger MD^c, S Villá MD PhD^b, N Viñolas MD^c, F Graus MD PhD^c,d, MD Ferrer PhD^a,d (a)Institut de Neuropatologia ICS, Bellvitge Hospital, (b)Ciutat Sanitària i Universitària de Bellvitge. (c) Hospital Clínic de Barcelona. (d)Universitat de Barcelona, Barcelona.
54	O6-Methylguanine-DNA methyltransferase (MGMT) protein expression in adult anaplastic glioma: relation to tumor and patient characteristics. A Tortosa MD PhD, M Brell MD, JJ Acebes MD PhD, L Caral MD, JM Gil MD, T Pujol MD, T Ribalta MD PhD, E Verger MD, S Villá MD PhD, N Viñolas MD, F Graus MD PhD, MD Ferrer PhD (1)Institut de Neuropatologia ICS, Bellvitge Hospital, (2)Ciutat Sanitària i Universitària de Bellvitge. (3) Hospital Clínic de Barcelona. (4)Universitat de Barcelona, Barcelona.
55	Real time RT-PCR for absolute quantification of hormone receptors in breast cancer C Caraion MD^a,b, N Vincent PhD^a, C Lambert MD^a, S Ursoniu MD PhD^b, C Genin MD PhD^a (a) Immunology Laboratory, Universitary Hospital of St. Etienne, France, (b) University of Medicine and Pharmacy of Timisoara, Romania
56	Up-regulation of stress inducible MICA on high-grade breast carcinomas Z Madjd MD^a, SE Pinder MD^b, PhD Spendlove^a, R Moss BSc^a, S Bevin MSc^a, LG Durrant PhD^a ^aCRC Clinical Oncology, ^bDept. of Histopathology; University of Nottingham, City Hospital, Nottingham, United Kingdom
57	Relatioship between HER-2/neu gene status and chemosensitivity of human endometrial cancer cell lines H Hiramatsu MD PhD, Y Kikuchi MD PhD, N Sasaki MD, S Okamoto MD, K Kudoh MD PhD, M Takano MD, T Kita MD PhD Department of Obstetrics and Gynecology, National Defense Medical College, Tokorozawa, Saitama, Japan
58	p16 and hMLH1 hypermethylation in synchronous endometrial and ovarian carcinomas D Furlan BSc, R Cerutti BSc, E Dainese MD, C Facco MD, C Riva MD, C Capella MD Department of Human Morphology, University of Insubria and Ospedale di Circolo, Varese, Italy
59	Non-invasive detection of bladder cancer using fluorescence in situ hybridization T Okamura MD PhD^a, Y Umemoto MD^a, T Yasui MD PhD^b, K Kohri MD PhD^b ^aThe Urology Division, Meijo Hospital, Nagoya, Japan, ^bDepartment of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
60	Comparative study of p53 immunoreactivity in benign and malignant prostate lesions A Ardakani MD, P Rajabi MD, H Javadzadeh MD, F Mohammadizadeh MD, H Baradaran (1) Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; (2) Department of Pathology, Western Infirmary Glasgow, University of Glasgow; (3) Department of Public Health and Health policy, University of Glasgow
61	Immunohistochemical expression of insulin-like growth factor binding protein-3 as a predictive marker for the response to hormonal therapy in patients with prostate cancer H Sakai MD, Y Miyata MD, T Igawa MD, T Hayashi MD, S Kanda MD, H Kanetake MD Nagasaki University School of Medicine, Nagasaki, Japan
62	The relationship between tyrosine-phosphorylated erbB-2 (p-erbB-2) expression and tumor development in patients with prostate cancer. Y Miyata MD, H Sakai MD PhD, S Kanda MD PhD, T Hakariya MD, T Igawa MD PhD, H Kanetake MD PhD Nagasaki Graduate University School of Medicine, Nagasaki, Japan
63	c-met, APC and P53 gene are sensitive molecular polymarkers for diagnosis of human gastric cancers in Taiwan W-S Tzou^a,b, J-Y Wang^a,c, C-H Wu^d, J-S Hsieh^c, T-J Huang^c, CPD Chen^e, K-F Huang^e, Y-S Chung^e, S-R Lin^a (a)MedicoGenomic Research Center, (b)School of Biotechnology, (c)Department of Surgery, (d)Institute of Medicine, Kaohsiung Medical University, Taiwan (e)Asia Hepato Gene Co., Ltd.
64	Quantitative and qualitative study of gastric epithelial lesions by NOR and lectin histochemistry MR Arab PhD, SA Sarani PhD, M Karimi MD, T Khoozani PhD Zahedan University of Medical Sciences, Zahedan, Iran
65	Microsatellite instability predicts relapse-free survival after adjuvant chemotherapy in patients with stage III colorectal cancer W Dietmaier PhD^a, M Woenckhaus^a, P Ruemmele^a, M Bettstetter^a, S Schilling^a, M Schalke^b, F Hofstaedter^a ^aUniversity of Regensburg, Institute of Pathology, Regensburg, Germany, ^bTumor Registry Regensburg, Regensburg, Germany
66	Mutations in the Ki-ras gene detected in colorectal biopsy specimens M Beranek PhD^a, J Bures Prof MD PhD^b, S Rejchrt MD PhD^b, K Dedic MD PhD^c, Prof Palicka MD PhD^a ^aInstitute of Clinical Biochemistry and Diagnostics, Charles University Hospital, Hradec Kralove, Czech Republic, ^bClinical Centre of Internal Medicine, ^cDepartment of Pathology; Charles University Hospital, Hradec Kralove, Czech Republic
67	Rapid and quantitative detection of human septin family Bradeion as a practical diagnostic method of colorectal and urologic cancers M Tanaka MD PhD^a, T Tanaka MD PhD^a, S Matsuzaki MSc^c, Y Seto MSc^d, T Matsuda MSc^a, K Komori MSc^a, J Itoh PhD^b, H Kijima MD PhD^b, K Tamai PhD^e, M Shibayama MSc^e, Y Hashimoto MD PhD^f, H Nakazawa MD PhD^f, H Toma MD PhD^f ^aNational Institute of Advanced Industrial Science and Technology, Ibaraki, Japan, ^bTokai University School of Medicine, Kanagawa, Japan, ^cNTC/Nippn Technocluster, Inc, Tokyo, Japan, ^dNippon Flour Mills Co, Ltd, Tokyo, Japan, ^eR&D Division, CycLex Co. Ltd, Nagano, Japan, ^fTokyo Women's Medical University, Tokyo, Japan
68	Prognostic significance of thymidylate synthase in colorectal cancer and comparison with DNA ploidy & other clinicopathological parameters NS Desai MSc, NH Karelia MD, SM Patel PhD, K Shah PhD Dept. of Pathology, Immunocytometry Division, Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, India